If you are looking for a way to stay awake while at work, then you may want to check out modafinil. This medication is used for several different reasons. But you should know the risks before using it. Read on to learn more about the common side effects of this drug, as well as its mechanism of action and interactions with other medications.
Mechanism of action
Buy Modafinil Australia has been approved for use by the Air Force for fatigue management. Although modafinil research is promising, the mechanism of action is not well understood.
While most studies of modafinil have investigated the reinforcing and pro-cognitive effects of modafinil, researchers have also examined the possible neurochemical mechanisms behind its cognitive effects. As a result, several targets for future study have been identified.
Some of the most important pharmacological targets for modafinil include dopamine, adrenergic, and 5-HT2A receptors. Several studies have investigated the interactions of modafinil with these receptors, as well as with cocaine and other drugs. Those findings have been published in the Journal of Pharmacology and Experimental Therapeutics.
Modafinil has been shown to improve working memory performance in mice. Similarly, it is effective at reducing excessive somnolence in patients with myotonic dystrophy. Furthermore, it has been found to protect against the degeneration of dopamine neurons in black mice.
Common side effects
Other drugs that you take at the same time as modafinil might reduce its effectiveness. These include some hormonal contraceptives and cyclosporine. Your physician should monitor you carefully to avoid these interactions.
Modafinil is often used to treat narcolepsy, a sleep disorder that causes an extreme amount of sleepiness. The drug is also used to treat shift work sleep disorder, a condition that affects the sleep pattern of workers who work in shifts.
Modafinil is also used to help patients with obstructive sleep apnea. The drug is primarily prescribed for daytime workers who need to remain awake during their shifts. However, it is also effective for nighttime workers.
Provigil, a brand of modafinil, is used to treat excessive sleepiness in people with narcolepsy. Buy Provigil Australia is available in 100-mg and 200-mg oral tablets. Taking too much modafinil can lead to side effects such as insomnia, agitation, and confusion.
Modafinil is considered safe when taken at recommended doses. But, there have been reports of severe and life-threatening side effects in people who have taken the medication. Symptoms include depression, mania, aggression, and thoughts of suicide.
Interactions with other medications
Modafinil is a novel wake-promoting agent approved by the United States Food and Drug Administration (FDA) as a schedule IV drug. It was first marketed in France in the early 1990s as a treatment for excessive somnolence in patients with narcolepsy. In addition to its effects on sleepiness, modafinil has been evaluated for sedation in other neurological disorders.
Several studies have shown that modafinil improves cognitive performance and vigilance in healthy adults and sleep-deprived subjects. In these studies, the effect is largely attributed to the activation of adrenergic and dopaminergic receptors. However, modafinil also exhibits activity-promoting properties, primarily involving catecholamine systems.
Modafinil has been studied in a wide range of illnesses, including narcolepsy, idiopathic generalized anxiety disorder, chronic schizophrenia, and a variety of other neuropsychiatric and neurological conditions. The results of these studies indicate that the drug has a well-tolerated profile, with relatively little risk of abuse.
Modafinil has been studied as an adjunct to selective serotonin reuptake inhibitors (SSRIs). SSRIs, such as fluoxetine and paroxetine, are known to increase extracellular serotonin levels. Adding modafinil to these treatments is thought to enhance the serotonin reuptake inhibitors’ effects. Moreover, modafinil has been found to improve attentional set-shifting in chronic schizophrenia. Click Here
